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Invitrogen™ MRP7 Polyclonal Antibody
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Catalog No. PIPA561008
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100 μL
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PIPA561008 100 μL
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Catalog No. PIPA561008 Supplier Invitrogen™ Supplier No. PA561008
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ILGMLSYTTR LLCTHRTEYL ERADAVLLME AGRLIRAGPP SEILPLVQAV PKAWAENGQE SDSATAQSVQ NPEKTKEGLE EEQSTSGRLL QEESKKE Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 72%.

The MRP family is represented by nine similar ABC transporters that have the ability to transport structurally diverse lipophilic anions and operate as chemical efflux pumps. MRP7 (multidrug resistance-associated protein 7, ATPbinding cassette sub-family C member 10) is a multi-pass membrane protein that belongs to the ABC transporter family (conjugate transporter subfamily). MRP7 is involved with the ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG). MRP7 is also probably involved in cellular detoxification through its lipophilic anion extrusion capabilities. MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains. MRP7 likely has three isoforms. Isoform 2 is the most widely expressed, while isoform 1 is predominately expressed in the spleen.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRP7
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ABCC10
Gene Accession No. Q5T3U5
Gene Alias ABCC10; ATP binding cassette subfamily C member 10; ATP-binding cassette sub-family C member 10; ATP-binding cassette, subfamily C (CFTR/MRP), member 10; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; EST182763; mFLJ00002; Mrp7; Multidrug resistance-associated protein 7; SIMRP7
Gene Symbols ABCC10
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MRP7. Recombinant protein control fragment (Product #RP-94747).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 89845
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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