MRP2 Monoclonal Antibody (M2III-5), Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA135678

Catalog No. 01-671-084

Description

For immunohistochemistry (paraffin) applications, it is recommended to pretreat antibody with 0.01 M citric acid, pH 6.0, in distilled water at 100oC 3 times for 5 minutes.

This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: MRP2
• Classification: Monoclonal
• Concentration: 250 μg/mL
• Formulation: tissue culture supernatant with 0.7% BSA and 0.1% sodium azide
• Gene Accession No.: Q92887
• Gene Symbols: ABCC2
• Immunogen: fusion protein of bacterial MBP and rat Mrp2, containing the 202-amino acid COOH terminal end
• Regulatory Status: RUO
• Gene ID (Entrez): 1244
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Clone: M2III-5
• Conjugate: Unconjugated
• Gene: ABCC2
• Gene Alias: ABC30; Abcc2; AI173996; ATP binding cassette subfamily C member 2; ATP-binding cassette sub-family C member 2; ATP-binding cassette, subfamily C (CFTR/MRP), member 2; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; calicular multispecific organic anion transporter; canalicular multidrug resistance protein; Canalicular multispecific organic anion transporter 1; Cmoat; CMOAT1; Cmrp; DJS; Human MRP2; KIAA1010; MRP2; multidrug resistance associated protein 2; multidrug resistance protein 2; multidrug resistance-associated protein 2
• Host Species: Mouse
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

Safety and Handling

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