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Invitrogen™ MRPL12 Polyclonal Antibody
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Catalog No. PIPA570707
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100 μL
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PIPA570707 100 μL
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Catalog No. PIPA570707 Supplier Invitrogen™ Supplier No. PA570707
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 79%.

MRPL12 (mitochondrial ribosomal protein L12), also referred to as 5c5-2, L12mt, MRPL7 or RPML12, is a mammalian mitochondrial ribosomal protein that is involved in protein synthesis within the mitochondrion. MRPL12 is enhanced in growth-stimulated cells as a result of transcriptional activation, suggesting that it may function as a translational regulator of mitochondrial mRNAs. Impairment of MRPL12 leads to reduction in cell growth rate, decreased mitochondrial ATP production and abolition of mitochondrial oxidative phosphorylation. MRPL12 is cleaved during its translocation across the mitochondrial membrane and it exists as dimers that bind the large ribosomal subunit. MRPL12 is 198 amino acids in length, belongs to the ribosomal protein L12P family and is highly expressed in the colon.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MRPL12
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene MRPL12
Gene Accession No. 0
Gene Alias 0610034O11Rik; 1500031N16Rik; 39S ribosomal protein L12, mitochondrial; 5c5-2; FLJ60124; hypothetical protein LOC550391; im:6893415; L12mt; MGC8610; Mitochondrial large ribosomal subunit protein bL12m; mitochondrial ribosomal protein L12; mitochondrial ribosomal protein L7/12; MRPL12; MRP-L12; MRP-L31/34; MRPL7; MRPL7/L12; ribosomal protein, mitochondrial, L12; Rpm12; RPML12; zgc:112445
Gene Symbols MRPL12
Host Species Rabbit
Immunogen synthetic peptide directed towards the middle region of rat MRPL12.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 303746
Target Species Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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