Invitrogen™ MRPL40 Polyclonal Antibody

Catalog No.	Quantity
PIPA585454	100 μL

Catalog No. PIPA585454 Supplier Invitrogen™ Supplier No. PA585454

Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (80%), Rat (80%), Rhesus Monkey (93%). Positive Control: A549, H1299, HCT-116. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.

Specifications

• Antigen: MRPL40
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.75 mg/mL
• Conjugate: Unconjugated
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene: MRPL40
• Gene Accession No.: P83565, Q9NQ50
• Gene Alias: 39S ribosomal protein L40, mitochondrial; L40mt; Mitochondrial large ribosomal subunit protein mL40; mitochondrial ribosomal protein L40; MRPL22; MRP-L22; Mrpl40; MRP-L40; Nlvcf; nuclear localization signal protein absent in velo-cardio-facial patients; nuclear localization signal-containing protein deleted in velocardiofacial syndrome; Nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog; up-regulated in metastasis; URIM
• Gene Symbols: MRPL40
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the center region of human MRPL40. The exact sequence is proprietary.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 287962, 64976
• Target Species: Human, Rat
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG