Invitrogen™ MRPL53 Polyclonal Antibody

Catalog No.	Quantity
PIPA5103530	100 μL

Catalog No. PIPA5103530

Supplier: Invitrogen™ PA5103530

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MRPL53.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL53 encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 1p.

Specifications

• Antigen: MRPL53
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: MRPL53
• Gene Accession No.: Q96EL3, Q9D1H8
• Gene Alias: 1110007K17Rik; 39S ribosomal protein L53, mitochondrial; L53MT; Mitochondrial large ribosomal subunit protein mL53; mitochondrial ribosomal protein L53; MRPL53; MRP-L53
• Gene Symbols: MRPL53
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human MRPL53(Accession Q96EL3), corresponding to amino acid residues K14-V64.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 116540, 362388, 68499
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov