MRPS15 Monoclonal Antibody (OTI6D2), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-1992	100 μL

Catalog No. 50-168-1992 Supplier OriGene Supplier No. TA808238

Description

Mouse Monoclonal Antibody

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS15 encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q.

Specifications

• Antigen: MRPS15
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI6D2
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: MRPS15
• Gene Accession No.: P82914
• Gene Alias: DC37, MPR-S15, RPMS15, S15mt
• Gene Symbols: MRPS15
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human MRPS15 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 64960
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b