Invitrogen™ MRPS21 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536487

Catalog No. PIPA536487

Description

This antibody detects endogenous protein at a molecular weight of 11 kDa. Purity is >95% by SDS-PAGE.

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S21P family. Pseudogenes corresponding to this gene are found on chromosomes 1p, 1q, 9p, 10p, 10q, 16q, and 17q. Available sequence data analyses identified splice variants that differ in the 5' UTR; both transcripts encode the same protein.

Specifications

• Antigen: MRPS21
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MRPS21
• Gene Alias: 1810031B19Rik; 28S ribosomal protein S21, mitochondrial; MDS016; mitochondrial 28S ribosomal protein S21; mitochondrial ribosomal protein S21; Mitochondrial small ribosomal subunit protein bS21m; MRPS21; MRP-S21; Rpms21; S21mt
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 54460, 66292, 689432
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P58059, P82921
• Gene Symbols: MRPS21
• Immunogen: Synthetic peptide corresponding to amino acids 41-87 of Human MRP-S21.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG