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Tocris Bioscience™ MSC 2032964A
SDP

Catalog No. 564110
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10 mg
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Catalog No. Quantity
56-411-0 10 mg
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Catalog No. 56-411-0 Supplier Tocris Bioscience™ Supplier No. 5641/10

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Description

Potent and selective ASK1 inhibitor; orally bioavailable

MSC 2032964A is a potent and selective ASK1 inhibitor (IC50 = 93 nM). Selective for ASK1 over a panel of 210 kinases. Blocks LPS-induced ASK1 and p38 phosphorylation in cultured mouse astrocytes. Suppresses neuroinflammation in a mouse EAE model. Orally bioavailable and brain penetrant.

Specifications

Chemical Name or Material N-[5-(Cyclopropylamino)-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]-3-pyridinecarboxamide
CAS 1124381-43-6
Quantity 10 mg
Target ASK1 Inhibitors
Molecular Formula C16H13F3N6O
Formula Weight 362.31
Purity >98%
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