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MSH3 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501570109
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20 μL; Unconjugated
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Catalog No.
50-157-0109 20 μL; Unconjugated
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Catalog No. 50-157-0109 Supplier Bethyl Laboratories, Inc Supplier No. A305314AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

Specifications

Antigen MSH3
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene MSH3
Gene Accession No. P20585
Gene Alias DUP, MRP1, DNA mismatch repair protein Msh3, divergent upstream protein, hMSH3, mismatch repair protein 1
Gene Symbols MSH3
Host Species Rabbit
Immunogen Between 1087 and 1137
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4437
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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