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MSH6 Mouse anti-Human, Clone: UMAB258, lyophilized, UltraMAB™
SDP

Catalog No. 501685422
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100 μg
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Catalog No. Quantity
50-168-5422 100 μg
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Catalog No. 50-168-5422 Supplier OriGene Supplier No. UM800148CF
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Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, domitly inherited disease associated with marked increase in cancer susceptibility. it is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.

Specifications

Antigen MSH6
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone UMAB258
Conjugate Unconjugated
Formulation PBS with 8% trehalose and no preservative; pH 7.3
Gene MSH6
Gene Accession No. P52701
Gene Alias GTBP, GTMBP, HNPCC5, HSAP, p160
Gene Symbols MSH6
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 1-280 of human MSH6 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2956
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG1
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