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MSH6 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501556754
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50-155-6754 20 μL
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Catalog No. 50-155-6754 Supplier Bethyl Laboratories, Inc Supplier No. A300023AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, domitly inherited disease associated with marked increase in cancer susceptibility. it is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.

Specifications

Antigen MSH6
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene MSH6
Gene Accession No. P52701
Gene Alias GTBP, HNPCC5, HSAP
Gene Symbols MSH6
Host Species Rabbit
Immunogen Between 1300 and C-term
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2956
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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