Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ MTA2 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA141581

Catalog No. 01-675-200


Only null left
Add to Cart

Description

Description

This antibody is predicted to react with mouse, rat, canine, bovine, and xenopus samples based on sequence homology. Suggested positive control: Jurkat cell lysate. Predicted cross-reactivity based on sequence identity: Dog/Bovine (88%) and Xenopus (76%).

This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MTA2
Polyclonal
Unconjugated
Mta2
AW550797; DKFZp686F2281; Mata1l1; metastais-associated gene family, member 2; metastasis associated 1 family member 2; metastasis associated 1 family, member 2; metastasis associated 1-like 1; metastasis -associated gene 1-like 1; metastasis associated gene family, member 2; metastasis-associated 1-like 1; metastasis-associated gene family, member 2; metastasis-associated protein 2; metastasis-associated protein MTA2; mmta2; Mta1l1; MTA1-L1 protein; Mta2; p53 target protein in deacetylase complex; PID
Rabbit
Antigen affinity chromatography
RUO
23942, 361724, 9219
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
O94776, Q9R190
Mta2
A portion of amino acids 650-700 of human MTA2.
100 μg
Primary
Human, Mouse, Rat, Monkey
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
Safety and Handling

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.