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Invitrogen™ MTHFD1 Polyclonal Antibody
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Catalog No. PIPA5110628
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PIPA5110628 100 μL
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Catalog No. PIPA5110628 Supplier Invitrogen™ Supplier No. PA5110628
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ILVVATGQPE MVKGEWIKPG AIVIDCGINY VPDDKKPNGR KVVGDVAYDE AKERASFITP VPGGVGPMTV AMLMQSTVES AKRFLEKFKP GKWMIQYNNL NLKTPVPSDI DISRSCKPKP IGKLAREIGL LSEEVELYGE TKAKVLLSAL EGAPHR Highest antigen sequence indentity to the following orthologs: Mouse - 90%, Rat - 90%.

This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MTHFD1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MTHFD1
Gene Accession No. P11586
Gene Alias 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methylenetetrahydrofolate cyclohydrolase, 10-formyltetrahydrofolate synthetase; C1-tetrahydrofolate synthase; C-1-tetrahydrofolate synthase, cytoplasmic; C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed; C1-THF synthase; cytoplasmic C-1-tetrahydrofolate synthase; Dcs; E430024A07Rik; Formyltetrahydrofolate synthetase; LOW QUALITY PROTEIN: C-1-tetrahydrofolate synthase, cytoplasmic; methenyltetrahydrofolate; methenyltetrahydrofolate cyclohydrolase; Methylenetetrahydrofolate dehydrogenase; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase; methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase; methylenetetrahydrofolate dehydrogenase 1; methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1; MTHFC; MTHFD; MTHFD1; MTHFD1 protein; formyltetrahydrofolate synthetase; methenyltetrahydrofolate cyclohydrolase,
Gene Symbols MTHFD1
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human MTHFD1. Recombinant protein control fragment (Product #RP-98840).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4522
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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