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Invitrogen™ MTHFD2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106331

Catalog No. PIPA5106331


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Description

Description

Antibody detects endogenous levels of total MTHFD2.

This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MTHFD2
Polyclonal
Unconjugated
MTHFD2
AW558851; Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase 2; Mthfd2; NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase; NAD-dependent methylenetetrahydrofolate dehydrogenase; NMDMC
Rabbit
Affinity chromatography
RUO
10797, 17768, 680308
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P13995, P18155
MTHFD2
A synthesized peptide derived from human MTHFD2(Accession P13995), corresponding to amino acid residues G42-A92.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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