ProSci MUC-17 Recombinant Protein

Catalog No.	Quantity
16-833-562	0.1 mg

Catalog No. 16-833-562 Supplier ProSci Supplier No. 111890100

Description

Recombinant Protein

This protein carries a polyhistidine tag at the C-terminus. This protein was cleaved within the SEA domain between 4243 Gly and 4244 Ser, and was cleaved into N and C-terminal fragment with calculated MW of 12.6 kDa and 18.6 kDa respectively. The protein

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

Specifications

• For Use With (Application): Western Blot
• Molecular Weight (g/mol): 31.2 kDa
• Quantity: 0.1 mg
• Source: Human Cells
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His Tag
• Sequence: Arg 4131 - Leu 4390
• Content And Storage: Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or-70°C. Avoid repeated freeze-thaw cycles.
• Purity or Quality Grade: >90% as determined by SDS-PAGE.
• Synonym: Mucin-17,MUC-17,MUC17,MUC-3,MUC3