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Invitrogen™ MUPP1 Polyclonal Antibody
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Catalog No. PIPA554168
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PIPA554168 100 μL
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Catalog No. PIPA554168 Supplier Invitrogen™ Supplier No. PA554168
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VVNILKELPI EVTMVCCRRT VPPTTQSELD SLDLCDIELT EKPHVDLGEF IGSSETEDPV LAMTDAGQST EEVQAPLAMW EAGIQHIELE KGSKGLGFS Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 82%.

MUPP1 (multi PDZ domain protein 1, MPDZ) was discovered as an interacting partner with the 5-HT2C receptor1, and was found to co-localize with 5-HT2A or 5-HT2C receptors in all regions of the mouse brain, including the choroid plexus. MUPP1 contains 13 PDZ domains but no apparent catalytic domain. MUPP1 is concentrated in tight junctions of polarized epithelial cells and binds to claudin-1 and junctional adhesion molecule (JAM). MUPP1 may therefore function as a multivalent scaffold protein that recruits various proteins to tight junctions. MUPP1 also interacts with claudin-8 and may play a role in tight junction barrier function.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MUPP1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MPDZ
Gene Accession No. O75970
Gene Alias AI225843; B930003D11Rik; DKFZp781P216; FLJ25909; FLJ34626; FLJ90240; HYC2; LOW QUALITY PROTEIN: multiple PDZ domain protein; MPDZ; Multi-PDZ domain protein 1; multiple PDZ domain crumbs cell polarity complex component; multiple PDZ domain protein; Mupp1
Gene Symbols MPDZ
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MUPP1. Recombinant protein control fragment (Product #RP-92907).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8777
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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