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Invitrogen™ MUPP1 Polyclonal Antibody
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Catalog No. 422700
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100 μg
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Catalog No. Quantity
42-270-0 100 μg
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Catalog No. 42-270-0 Supplier Invitrogen™ Supplier No. 422700
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Description

Rabbit Polyclonal Antibody

MUPP1 Polyclonal Antibody for Western Blot, IHC (F)

MUPP1 (multi PDZ domain protein 1, MPDZ) was discovered as an interacting partner with the 5-HT2C receptor1, and was found to co-localize with 5-HT2A or 5-HT2C receptors in all regions of the mouse brain, including the choroid plexus. MUPP1 contains 13 PDZ domains but no apparent catalytic domain. MUPP1 is concentrated in tight junctions of polarized epithelial cells and binds to claudin-1 and junctional adhesion molecule (JAM). MUPP1 may therefore function as a multivalent scaffold protein that recruits various proteins to tight junctions. MUPP1 also interacts with claudin-8 and may play a role in tight junction barrier function.
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Specifications

Antigen MUPP1
Applications Immunohistochemistry (Frozen), Western Blot
Classification Polyclonal
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene MPDZ
Gene Accession No. Q8VBX6
Gene Alias AI225843; B930003D11Rik; DKFZp781P216; FLJ25909; FLJ34626; FLJ90240; HYC2; LOW QUALITY PROTEIN: multiple PDZ domain protein; MPDZ; Multi-PDZ domain protein 1; multiple PDZ domain crumbs cell polarity complex component; multiple PDZ domain protein; Mupp1
Gene Symbols MPDZ
Host Species Rabbit
Immunogen Synthetic peptide derived from the C-terminal region of mouse MUPP1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17475
Target Species Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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