Invitrogen™ MURF1 Monoclonal Antibody (M316)

Catalog No.	Quantity
PIMA547723	100 μL

Catalog No. PIMA547723

Supplier: Invitrogen™ MA547723

Description

Mouse Monoclonal Antibody

The antibody detects a full length human MuRF1 recombinant protein on SDS-PAGE immunoblots.

This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle.

Specifications

• Antigen: MURF1
• Applications: Western Blot
• Classification: Monoclonal
• Clone: M316
• Concentration: 2.0 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
• Gene: TRIM63
• Gene Accession No.: Q38HM4, Q91Z63, Q969Q1
• Gene Alias: E3 ubiquitin-protein ligase TRIM63; FLJ32380; IRF; iris ring finger protein; Murf; MURF 1; MuRF1; MuRF-1; MURF2; muscle ring finger protein 1; muscle specific ring finger protein 2; muscle-specific RING finger protein 1; OTTHUMP00000008701; RF1; ring finger protein 28; RING-type E3 ubiquitin transferase TRIM63; RNF 28; RNF28; SMRZ; striated muscle RING zinc finger protein; TRIM 63; Trim63; tripartite motif containing 63; tripartite motif containing 63, E3 ubiquitin protein ligase; tripartite motif protein 63; tripartite motif-containing 63; tripartite motif-containing protein 63
• Gene Symbols: TRIM63
• Host Species: Mouse
• Immunogen: Clone M316 was generated from a synthetic peptide (coupled to KLH) corresponding to amino acid residues in the C-terminal half of human MuRF1. This peptide sequence is highly conserved in rat and mouse MuRF1, and has 50% homology to MuRF2 (TRIM-55).
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 140939, 433766, 84676
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1