Invitrogen™ BMP-4 Monoclonal Antibody, PeproTech®

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ 500M121500UG

Catalog No. 50-162-6189

Description

AA Sequence of recombinant protein: HHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP TELSAISMLY LDEYDKVVLK NYQEMVVEGC GCR. Preparation: Produced in mice immunized with highly pure Recombinant Human BMP-4. Anti-Human BMP-4-specific antibody was purified from cell culture by Protein G affinity chromatography.

The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Specifications

• Antigen: BMP-4
• Classification: Monoclonal
• Formulation: PBS with no preservative
• Gene Accession No.: P12644
• Gene Symbols: BMP4
• Immunogen: HeLa cells-derived Recombinant Human BMP-4.
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody

• Applications: ELISA, Western Blot
• Conjugate: Unconjugated
• Gene: BMP4
• Gene Alias: BMP; BMP2B; BMP-2B; Bmp2b1; Bmp2b-1; Bmp4; Bmp-4; BOMPR4A; Bone morphogenetic protein; Bone morphogenetic protein 2B; bone morphogenetic protein 4; bone morphogenetic protein 4 preproprotein; DVR4; Dvr-4; MCOPS6; OFC11; ZYME
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 652
• Content And Storage: -20°C
• Form: Lyophilized