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Invitrogen™ MUSK Polyclonal Antibody
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Catalog No. PA11741
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200 μg
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Catalog No. Quantity
PA11741 200 μg
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Catalog No. PA11741 Supplier Invitrogen™ Supplier No. PA11741
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Description

Rabbit Polyclonal Antibody

PA1-1741 detects a predominant band at ~98kD. Other lower MW nonspecific bands of unknown identity were also detected and are likely to be proteolytic fragments.

MUSK plays an important and selective role in many aspects of skeletal muscle development and function through the initial step of postsynaptic differentiation and formation of end-plate bands in cooperation with Rapsyn. Communication between cells is often mediated by receptors on the surface of the target cell that are triggered by specific ligands released by other cells. Receptor tyrosine kinase activity is strictly regulated by the binding of the appropriate ligand to the extracellular active site of the receptor. MuSK has been shown to be part of the agrin signaling complex and plays an important role in the development and architectural maintenance of the neuromuscular junction.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MUSK
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide
Gene MUSK
Gene Accession No. O15146, Q61006, Q62838
Gene Alias CMS9; FADS; Mdk4; MGC126323; MGC126324; Mlk; muscle associated receptor tyrosine kinase; muscle localized kinase 2; muscle specific kinase (neural fold/somite kinase 1); muscle, skeletal receptor tyrosine protein kinase; Muscle, skeletal receptor tyrosine-protein kinase; muscle, skeletal, receptor tyrosine kinase; muscle-specific kinase receptor; muscle-specific protein kinase secretory isoform; muscle-specific tyrosine kinase receptor MuSK; muscle-specific tyrosine protein kinase receptor; Muscle-specific tyrosine-protein kinase receptor; MuSK; Nsk1; Nsk2; Nsk3; RP23-170A3.1
Gene Symbols MUSK
Host Species Rabbit
Immunogen Recombinant protein containing residues 210-304 from the extracellular domain of rat MuSK.
Purification Method Protein G
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18198, 4593, 81725
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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