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Invitrogen™ MUSK Recombinant Rabbit Monoclonal Antibody (PSH05-68)
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Catalog No. MA552463
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MA552463 100 μL
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Catalog No. MA552463 Supplier Invitrogen™ Supplier No. MA552463
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: Mouse skeletal muscle tissue lysate, rat skeletal muscle tissue lysate, human skeletal muscle tissue, mouse skeletal muscle tissue, rat skeletal muscle tissue. Sequence Similarities: 100% Mouse/Rat. Subcellular Location: Postsynaptic cell membrane. Predicted band size: 97 kDa.

MUSK plays an important and selective role in many aspects of skeletal muscle development and function through the initial step of postsynaptic differentiation and formation of end-plate bands in cooperation with Rapsyn. Communication between cells is often mediated by receptors on the surface of the target cell that are triggered by specific ligands released by other cells. Receptor tyrosine kinase activity is strictly regulated by the binding of the appropriate ligand to the extracellular active site of the receptor. MuSK has been shown to be part of the agrin signaling complex and plays an important role in the development and architectural maintenance of the neuromuscular junction.
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Specifications

Antigen MUSK
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone PSH05-68
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol, 0.1% BSA and 0.05% sodium azide; pH 7.4
Gene MUSK
Gene Accession No. O15146, Q61006, Q62838
Gene Alias CMS9; FADS; Mdk4; MGC126323; MGC126324; Mlk; muscle associated receptor tyrosine kinase; muscle localized kinase 2; muscle specific kinase (neural fold/somite kinase 1); muscle, skeletal receptor tyrosine protein kinase; Muscle, skeletal receptor tyrosine-protein kinase; muscle, skeletal, receptor tyrosine kinase; muscle-specific kinase receptor; muscle-specific protein kinase secretory isoform; muscle-specific tyrosine kinase receptor MuSK; muscle-specific tyrosine protein kinase receptor; Muscle-specific tyrosine-protein kinase receptor; MuSK; Nsk1; Nsk2; Nsk3; RP23-170A3.1
Gene Symbols MUSK
Host Species Rabbit
Immunogen Recombinant protein within human musk aa 1-516/869.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18198, 4593, 81725
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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