Invitrogen™ MVP Monoclonal Antibody (LMR5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA135590

Catalog No. 01-671-028

Description

LMR5 reacts with an internal epitope of the LRP/Major Vault Protein (P110), which is strongly overexpressed in various human non-P-glycoprotein MDR tumor cell lines.

This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.

Specifications

• Antigen: MVP
• Classification: Monoclonal
• Concentration: 0.25 mg/mL
• Formulation: Tissue culture supernatant with 1% BSA and 0.1% sodium azide
• Gene Accession No.: Q14764
• Gene Symbols: MVP
• Immunogen: Proprietary Immunogen.
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
• Clone: LMR5
• Conjugate: Unconjugated
• Gene: MVP
• Gene Alias: 2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP
• Host Species: Mouse
• Purification Method: purified
• Regulatory Status: RUO
• Gene ID (Entrez): 9961
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov