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Invitrogen™ MVP Monoclonal Antibody (LMR5)
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Catalog No. 01671028
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01-671-028 1 mL
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Catalog No. 01-671-028 Supplier Invitrogen™ Supplier No. MA135590
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Description

Mouse Monoclonal Antibody

LMR5 reacts with an internal epitope of the LRP/Major Vault Protein (P110), which is strongly overexpressed in various human non-P-glycoprotein MDR tumor cell lines.

This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MVP
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone LMR5
Concentration 0.25 mg/mL
Conjugate Unconjugated
Formulation Tissue culture supernatant with 1% BSA and 0.1% sodium azide
Gene MVP
Gene Accession No. Q14764
Gene Alias 2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP
Gene Symbols MVP
Host Species Mouse
Immunogen Proprietary Immunogen.
Purification Method purified
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9961
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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