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Invitrogen™ MVP Monoclonal Antibody (LRP-56)
Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA135743
Description
LRP-56 reacts with an internal epitope of the LRP-protein (P110), which is strongly over-expressed in various human non-P-glycoprotein MDR tumor cell lines.
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
Specifications
MVP | |
Monoclonal | |
0.1 mg/mL | |
Tissue culture supernatant with 1% BSA and 0.1% sodium azide | |
Q14764 | |
MVP | |
Proprietary immunogen. | |
1 mL | |
Primary | |
Human | |
Antibody | |
IgG2b |
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunocytochemistry | |
LRP-56 | |
Unconjugated | |
MVP | |
2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP | |
Mouse | |
purified | |
RUO | |
9961 | |
4°C | |
Liquid |
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