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Invitrogen™ MVP Polyclonal Antibody
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Catalog No. PIPA522296
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100 μL
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PIPA522296 100 μL
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Catalog No. PIPA522296 Supplier Invitrogen™ Supplier No. PA522296
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HeLa, Molt-4, Neuro2A, GL261, C8D30, BCL-1, Raw264.7. Predicted reactivity: Mouse (90%), Rat (90%), Dog (91%), Cat (93%), Bovine (88%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MVP
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene MVP
Gene Accession No. Q14764
Gene Alias 2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP
Gene Symbols MVP
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human MVP/LRP. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9961
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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