MYBPC2 Monoclonal Antibody (OTI2E1), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-3902	100 μL

Catalog No. 50-168-3902 Supplier OriGene Supplier No. TA811203

Description

Mouse Monoclonal Antibody

Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the fast-type isoform designated MYBPC2. Both the fast-type and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. MYBPC2 is typically required for strong contractions and functions under anaerobic conditions. It is more similar to the cardiac isoform (MYBPC3) than to the slow-type isoform (MYBPC1) in terms of pCa50-indexed force development, length-independent cooperativity and length dependent activation. It has been suggested that in cardiac and fast muscle MYBPC2 contributes to an internal load, possibly by binding to actin via its N-terminal region.

Specifications

• Antigen: MYBPC2
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI2E1
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: MYBPC2
• Gene Accession No.: Q14324
• Gene Alias: MYBPC, MYBPCF
• Gene Symbols: MYBPC2
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human MYBPC2 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4606
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1