Invitrogen™ MYBPC3 Polyclonal Antibody

Catalog No.	Quantity
PIPA579714	100 μg

Catalog No. PIPA579714 Supplier Invitrogen™ Supplier No. PA579714

Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat heart tissue, mouse heart tissue. IHC: rat heart tissue, human lung cancer tissue, human mammary cancer tissue, human rectal cancer tissue.

Myosin binding protein C, cardiac-type (MYBPC3) is a thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments. It modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Mutations affecting the gene can result in cardiomyopathy - familial hypertrophic 4, cardiomyopathy - dilated 1MM, or left ventricular non-compaction 10.

Specifications

• Antigen: MYBPC3
• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and no preservative
• Gene: MYBPC3
• Gene Accession No.: O70468, P56741, Q14896
• Gene Alias: cardiac C-protein; cardiac MyBP-C; cardiac myosin binding protein C; CMD1MM; CMH4; C-protein, cardiac muscle isoform; DKFZp779E1762; FHC; LVNC10; MYBP-C; Mybpc3; myosin binding protein C, cardiac; myosin binding protein C3; myosin-binding protein C, cardiac-type; truncated cardiac myosin-binding protein C
• Gene Symbols: MYBPC3
• Host Species: Rabbit
• Immunogen: E. coli-derived human MYBPC3 recombinant protein (Position: Q1070-H1123).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 17868, 295929, 4607
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG