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Invitrogen™ Myc Tag Polyclonal Antibody
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Catalog No. 01670202
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100 μg
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Catalog No. Quantity
01-670-202 100 μg
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Catalog No. 01-670-202 Supplier Invitrogen™ Supplier No. PA3981
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Description

Sheep Polyclonal Antibody

PA3-981 detects c-Myc tagged proteins. PA3-981 has been successfully used in immunofluorescence, immunoprecipitation, and Western blot procedures. By Western blot it detects a ~41 kDa protein representing c-Myc. The PA3-981 immunogen is a synthetic peptide corresponding to residues M E Q K L I S E E D L G C of human c-Myc.

Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Myc Tag
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide; pH 7.4
Gene MYC
Gene Accession No. P01106
Gene Alias 46-0603; AU016757; avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; class E basic helix-loop-helix protein 39; cmyc; c-Myc; c-myc epitope tag; c-myc proto-oncogene; MRTL; MYC; Myc protein; Myc proto-oncogene protein; Myc Tag; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; Niard; Nird; Proto-oncogene c-Myc; R95025; R950-25; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols MYC
Host Species Sheep
Immunogen Synthetic peptide corresponding to residues M E Q K L I S E E D L G C of human c-Myc.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4609
Target Species Tag
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Target Molecule Tag
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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