Mycophenolic acid, 98%

Catalog No.	Quantity
AAJ6190503	1 g
AAJ6190506	5 g
AAJ6190509	10 g

Catalog No. AAJ6190503 Supplier Thermo Scientific Chemicals Supplier No. J6190503

Description

CAS: 24280-93-1 | C17H20O6 | 320.341 g/mol

It is used as a small molecule IMPDH inhibitor. mycophenolic Acid is used as an immunosuppressive agent with antiviral and antitumor effects. It potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. It also reversibly inhibits proliferation of T and B lymphocytes and antibody formation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as a small molecule IMPDH inhibitor. mycophenolic Acid is used as an immunosuppressive agent with antiviral and antitumor effects. It potently inhibits inosine monophosphate dehydrogenase, thus inhibiting de novo GTP synthesis leading to decreased RNA and DNA synthesis. It also reversibly inhibits proliferation of T and B lymphocytes and antibody formation.

Solubility
Soluble in methanol at 50mg/ml

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C. Keep away from strong oxidizing agent.

Specifications

Chemical Identifiers

• CAS: 24280-93-1
• Molecular Formula: C17H20O6
• Molecular Weight (g/mol): 320.341
• MDL Number: MFCD00036814
• InChI Key: HPNSFSBZBAHARI-RUDMXATFSA-N
• Synonym: mycophenolic acid, mycophenolate, melbex, myfortic, mycophenolsaeure, acido micofenolico, micofenolico acido, acide mycophenolique, acidum mycophenolicum, 6-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl-4-methyl-4-hexenoic acid
• PubChem CID: 446541
• ChEBI: CHEBI:168396
• IUPAC Name: (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
• SMILES: CC1=C(C(=C(C2=C1COC2=O)O)CC=C(C)CCC(=O)O)OC

• Melting Point: 139°C to 141°C
• Color: White
• Quantity: 1 g
• Beilstein: 1295848
• Merck Index: 14,6327
• Solubility Information: Soluble in methanol at 50mg/ml
• Formula Weight: 320.34
• Percent Purity: 98%
• Physical Form: Powder
• Chemical Name or Material: Mycophenolic acid

Safety and Handling

Hazard Category	H302-H341-H360D-H372
Hazard Statement	GHS H Statement H302 Harmful if swallowed.
Precautionary Statement	P201-P202-P260-P264b-P270-P281-P301+P312-P308+P313-P330-P501c
DOTInformation	Hazard Class: 9; Packaging Group: III
EINECSNumber	246-119-3
RTECSNumber	MP8050000
TSCA	No
Recommended Storage	Store at -20°C

SDS

RUO – Research Use Only