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CPC Scientific H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Pro-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH (trifluoroacetate salt) 0.5MG
Supplier: CPC Scientific MOG002A
In contrast to the encephalitogenic rat homolog, this peptide is not a major T-cell epitope in multiple sclerosis propably due to its lower amount of helical structure formed when dissolved in micellar sodium dodecyl sulfate. This peptide induced anti-MOG(35-55) autoantibody production in C57BL/6 mice.ONE-LETTER SEQUENCE: MEVGWYRPPFSRVVHLYRNGKMOLECULAR FORMULA: C120H179N35O28S1MOLECULAR WEIGHT:2592.03STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [163158-19-8], RESEARCH AREA: Multiple SclerosisREFERENCES: N.Kerlero de Rosbo et al., Eur. J. Immunol., 27, 3059 (1997); S.Albouz-Abo et al., Eur. J. Biochem., 246, 59 (1997); M.F.Mesleh et al., Neurobiol. Dis., 9, 160 (2002); Oliver, A. J. Immunology 171, 462 (2003); Stromnes, I. et al. Nature protocols 1, 1810 (2006)
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