Invitrogen™ MYH6 Monoclonal Antibody (CL2162)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524633

Catalog No. PIMA524633

Description

Immunogen sequence: QVEEDKVNSL SKSKVKLEQQ VDDLEGSLEQ EKKVRMDLER AKRKLEGDLK LTQESIMDLE NDKLQLEEKL KKKEFDINQQ NSKIEDEQVL ALQLQKKLKE NQARIEELEE ELEAERTARA KVEKLRSDLS RELEEISERL EEA Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 96%. Binds to an epitope located within the peptide sequence RELEEISERLEEA as determined by overlapping synthetic peptides.

Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located approximately 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.

Specifications

• Antigen: MYH6
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P13533
• Gene Symbols: MYH6
• Immunogen: Recombinant protein corresponding to Human MYBPC2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: CL2162
• Conjugate: Unconjugated
• Gene: MYH6
• Gene Alias: A830009F23Rik; AA517445; alpha cardiac MHC; alpha myosin; alpha-MHC; ASD3; cardiac myosin heavy chain alpha isoform; cardiomyopathy, hypertrophic 1; CMD1EE; CMH14; MYH6; MYHC; Myhca; Myhc-a; MyHC-alpha; myosin 6; Myosin heavy chain 6; myosin heavy chain polypeptide 6 cardiac muscle adult; myosin heavy chain, cardiac muscle alpha isoform; Myosin heavy chain, cardiac muscle alpha isoform (MyHC-alpha); myosin heavy chain, cardiac muscle, adult; myosin heavy chain, polypeptide 6, cardiac muscle, alpha; myosin, heavy chain 6, cardiac muscle, alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha; myosin, heavy polypeptide 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1); myosin-6; SSS3
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4624
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid