Myo18A/Myosin XVIIIA Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A301598AT

Catalog No. 50-156-0792

Description

The recommended shelf life for this product is 1 year from date of receipt.

MYO18A may link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintece of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking.

Specifications

• Antigen: Myo18A/Myosin XVIIIA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYO18A
• Gene Alias: KIAA0216, MAJN, molecule associated with JAK3 N-terminus, myosin 18A, myosin containing a PDZ domain, myosin containing PDZ domain, myosin-XVIIIa, MysPDZ, SP-A receptor subunit SP-R210 alphaS, SPR210
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 399687
• Content And Storage: 4° C
• Form: Liquid

• Applications: Immunoprecipitation
• Concentration: 1 mg/ml
• Formulation: phosphate, tris citrate with 0.09% sodium azide; pH 7-8
• Gene Accession No.: Q92614
• Gene Symbols: MYO18A
• Immunogen: Between 2004 and 2054
• Quantity: 10 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG