Invitrogen™ MYOD Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA523078

Catalog No. PIPA523078

Description

The target sequence has 90% sequence homology with mouse.

The Myogenic determination gene (MyoD) was first identified by the virtue of its ability to convert embryonic mouse fibroblast cells to muscle cells. It was subsequently shown that forced expression of MyoD (human homolog is myf 3) gene in a wide variety of normal and neoplastic cells could either convert the cells to muscle cells or activate a set of the otherwise transcriptionally inactive muscle-specific genes in these cells. The regulatory domain of the MyoD gene product lies within a 70 amino acid region and comprises a basic DNA binding motif and a helix-loop-helix (HLH) dimerization motif. Subsequent studies identified three other genes whose products shared sequence homology for the basic HLH domain of MyoD. These are; myf5, myogenin (human homolog is myf4) and myf6 (also known as MRF4 and herculin).

Specifications

• Antigen: MYOD
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYOD1
• Gene Alias: AI503393; bHLHc1; Class C basic helix-loop-helix protein 1; CMD1; MYF3; Myf-3; Myoblast determination protein 1; myoblast determination protein 1 homolog; Myod; MYOD1; Myod-1; MYOD1 homolog; myogenic differentiation 1; myogenic factor 1; myogenic factor 3; PUM; unnamed protein product
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17927, 4654
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1.0 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: P10085, P15172
• Gene Symbols: MYOD1
• Immunogen: A synthetic peptide made to an N-terminal region of the human MyoD1 protein (within residues 1-150).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov