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MYOD Polyclonal Antibody, Invitrogen™

Catalog No. PIPA5110006
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PIPA5110006 100 μL
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Catalog No. PIPA5110006 Supplier Thermo Scientific Supplier No. PA5110006

Description

Rabbit Polyclonal Antibody

Immunogen sequence: YEGAYYNEAP SEPRPGKSAA VSSLDCLSSI VERISTESPA APALLLADVP SESPPRRQEA AAPSEGESSG DPTQS

The Myogenic determination gene (MyoD) was first identified by the virtue of its ability to convert embryonic mouse fibroblast cells to muscle cells. It was subsequently shown that forced expression of MyoD (human homolog is myf 3) gene in a wide variety of normal and neoplastic cells could either convert the cells to muscle cells or activate a set of the otherwise transcriptionally inactive muscle-specific genes in these cells. The regulatory domain of the MyoD gene product lies within a 70 amino acid region and comprises a basic DNA binding motif and a helix-loop-helix (HLH) dimerization motif. Subsequent studies identified three other genes whose products shared sequence homology for the basic HLH domain of MyoD. These are; myf5, myogenin (human homolog is myf4) and myf6 (also known as MRF4 and herculin).
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYOD
Applications Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 1.07 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MYOD1
Gene Accession No. P10085, P15172, Q02346
Gene Alias AI503393; bHLHc1; Class C basic helix-loop-helix protein 1; CMD1; MYF3; Myf-3; Myoblast determination protein 1; myoblast determination protein 1 homolog; Myod; MYOD1; Myod-1; MYOD1 homolog; myogenic differentiation 1; myogenic factor 1; myogenic factor 3; PUM; unnamed protein product
Gene Symbols MYOD1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 226-300 of human MyoD1 (NP_0024692)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17927, 337868, 4654
Target Species Human, Mouse, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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