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MYOD1 Mouse anti-Human, Clone: 5D1D12, Proteintech
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Catalog No. 501736647 Shop All Proteintech Group Inc Products
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50-173-6647 150 μL
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Catalog No. 50-173-6647 Supplier Proteintech Group Inc Supplier No. 662141IG150UL
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Mouse Monoclonal Antibody

The Myogenic determination gene (MyoD) was first identified by the virtue of its ability to convert embryonic mouse fibroblast cells to muscle cells. It was subsequently shown that forced expression of MyoD (human homolog is myf 3) gene in a wide variety of normal and neoplastic cells could either convert the cells to muscle cells or activate a set of the otherwise transcriptionally inactive muscle-specific genes in these cells. The regulatory domain of the MyoD gene product lies within a 70 amino acid region and comprises a basic DNA binding motif and a helix-loop-helix (HLH) dimerization motif. Subsequent studies identified three other genes whose products shared sequence homology for the basic HLH domain of MyoD. These are; myf5, myogenin (human homolog is myf4) and myf6 (also known as MRF4 and herculin).

Specifications

Antigen MYOD1
Applications Western Blot
Classification Monoclonal
Clone 5D1D12
Concentration 1.47 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MYOD1
Gene Accession No. P15172
Gene Alias bHLHc1, Myf 3, MYF3, MYOD, MYOD1, myogenic differentiation 1, Myogenic factor 3, PUM
Gene Symbols MYOD1
Host Species Mouse
Immunogen MYOD1 Fusion Protein Ag13512
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4654
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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