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Myogenin Monoclonal Antibody (F5D), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

$147.65 - $462.00

Specifications

Antigen Myogenin
Clone F5D
Concentration 0.5 mg/mL
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-131-11
Encompass_Preferred
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LIFE TECHNOLOGIES
14564380
25 μg
Each for $147.65

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Reg : $196.00

The following deviations and disclosures may produce prices below stated discounts but will not trigger price reductions: Price shown reflects a temporary, promotional price reduction. No other purchase or commercial obligation required to receive the reduced price. Price may change at any time. Promotional price valid on web orders only. Your contract pricing may differ. Other exclusions apply.
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50-131-12
Encompass_Preferred
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LIFE TECHNOLOGIES
14564382
100 μg
Each for $462.00
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Description

Description

Description: This F5D monoclonal antibody reacts with human, mouse, dog, and rat myogenin, a 34-kDa transcription factor. Expressed in skeletal and heart muscle, myogenin is a member of the MyoD family of basic-helix-loop-helix proteins, which also includes MyoD, Myf5, and MRF4. This transcription factor interacts with other helix-loop-helix proteins, which may or may not be muscle-specific. Myogenin plays a significant role in myogenic differentiation, even directing nonmuscle cells to the myogenic lineage. Transforming growth factor-beta (TGFb) and bone morphogenetic protein-2 (BMP2) inhibit myogenin transcriptional activity. Predomitly residing within the nucleus, the subcellular localization of myogenin has been shown to be dependent on differentiation status and cell density. For instance, trafficking of myogenin between the nucleus and cytoplasm has been reported during skeletal muscle differentiation to mediate transcription control. Applications Reported: This F5D antibody has been reported for use in immunoblotting (WB) and immunocytochemistry. Applications Tested: This F5D antibody has been tested by western blot and immunocytochemistry of the C2C12 cell line. This can be used at less than or equal to 1-5 μg/mL for both applications. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC.

Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix proteins. It is essential for the development of functional skeletal muscle.
Specifications

Specifications

Myogenin
0.5 mg/mL
Monoclonal
Liquid
RUO
PBS with 0.09% sodium azide; pH 7.2
bHLHc3; Class C basic helix-loop-helix protein 3; MYF4; Myf-4; myo; MYOD1-related protein; MYOG; Myogenic factor 4; Myogenic factor-4; myogenin; myogenin (myogenic factor 4)
MYOG
Primary
4°C
MYOG
F5D
Western Blot, Immunocytochemistry
Unconjugated
Mouse
Human, Mouse, Rat, Canine
P12979, P15173, P20428
17928, 29148, 4656, 490224
IgG1
Affinity Chromatography
Antibody
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