N-Boc-propargylamine, 97%

Description

CAS: 92136-39-5 | C8H13NO2 | 155.197 g/mol

N-Boc-propargylamine is used to prepare triazolobenzylidene-thiazolopyrimidines. which act as CDC25 phosphatase inhibitors. Further, it is used for the synthesis of beta-glucan polysaccharide analogs. In addition to this, it is involved in the Pauson-Khand (PK) reaction of norbornadiene and N-Boc-propargylamine to prepare 4,5-disubstituted cyclopentenones .

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Boc-propargylamine is used to prepare triazolobenzylidene-thiazolopyrimidines. which act as CDC25 phosphatase inhibitors. Further, it is used for the synthesis of beta-glucan polysaccharide analogs. In addition to this, it is involved in the Pauson-Khand (PK) reaction of norbornadiene and N-Boc-propargylamine to prepare 4,5-disubstituted cyclopentenones .

Solubility
Soluble in chloroform.

Notes
Moisture sensitive. Incompatible with oxidizing agents. Store in a cool place.

Specifications

Chemical Identifiers

• CAS: 92136-39-5
• Molecular Formula: C8H13NO2
• Molecular Weight (g/mol): 155.197
• MDL Number: MFCD07367245
• InChI Key: DSPYCWLYGXGJNJ-UHFFFAOYSA-N
• Synonym: n-boc-propargylamine, n-tert-butoxycarbonyl propargylamine, n-boc-prop-2-ynylamine, tert-butyl prop-2-yn-1-ylcarbamate, n-boc-propargyl amine, tert-butyl n-prop-2-yn-1-yl carbamate, tert-butyl prop-2-ynylcarbamate, n-boc-2-propyn-1-amine, n-boc propargyl amine, prop-2-ynyl-carbamic acid tert-butyl ester
• PubChem CID: 11073648
• IUPAC Name: tert-butyl N-prop-2-ynylcarbamate
• SMILES: CC(C)(C)OC(=O)NCC#C

• Melting Point: 40°C to 44°C
• Linear Formula: HC≡CCH₂NHCO₂C(CH₃)₃
• Solubility Information: Soluble in chloroform.
• Quantity: 5 g
• Flash Point: 93°C (199°F)
• Formula Weight: 155.2
• Sensitivity: Moisture sensitive
• Percent Purity: 97%
• Chemical Name or Material: N-Boc-propargylamine

Safety and Handling

Hazard Category	H302-H315-H319-H335
Hazard Statement	GHS H Statement H302-H315-H319-H335 Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
TSCA	No
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only