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N-Methyl-N-(trimethylsilyl)trifluoroacetamide, 97%

Catalog No. AAA1314106
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Catalog No. AAA1314106 Supplier Thermo Scientific Chemicals Supplier No. A1314106
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CAS: 24589-78-4 | C6H12F3NOSi | 199.25 g/mol

N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.

Solubility
Immiscible with water.

Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong acids.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 24589-78-4
Molecular Formula C6H12F3NOSi
Molecular Weight (g/mol) 199.25
MDL Number MFCD00000411
InChI Key MSPCIZMDDUQPGJ-UHFFFAOYSA-N
Synonym mstfa, n-methyl-n-trimethylsilyl trifluoroacetamide, 2,2,2-trifluoro-n-methyl-n-trimethylsilyl acetamide, n-methyl-n-trimethylsilyltrifluoroacetamide, acetamide, 2,2,2-trifluoro-n-methyl-n-trimethylsilyl, n-methyl-n-trimethylsilyl-trifluoroacetamide, acmc-209tfm
PubChem CID 32510
ChEBI CHEBI:85064
IUPAC Name 2,2,2-trifluoro-N-methyl-N-trimethylsilylacetamide
SMILES CN(C(=O)C(F)(F)F)[Si](C)(C)C

Specifications

Density 1.076
Boiling Point 130°C to 132°C
Flash Point 25°C (77°F)
Refractive Index 1.38
Quantity 5 g
UN Number UN1993
Beilstein 1941550
Sensitivity Moisture sensitive
Solubility Information Immiscible with water.
Formula Weight 199.25
Percent Purity 97%
Chemical Name or Material N-Methyl-N-(trimethylsilyl)trifluoroacetamide
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Hazard Category H226-H315-H319-H335
Hazard Statement GHS H Statement
H226-H315-H319-H335
Flammable liquid and vapour.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c
DOTInformation Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, N.O.S.
EINECSNumber 246-331-6
RTECSNumber AC9800000
TSCA Yes
Recommended Storage Ambient temperatures

RUO – Research Use Only

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