N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS

Description

CAS: 25561-30-2 | C8H18F3NOSi2 | 257.403 g/mol

N,O-Bis(trimethylsilyl)trifluoroacetamide is used as a derivatization reagent for gas chromatography and mass-spectrometry analysis of phenolic acids in fruits. It is also used as a reactant in the preparation of pyrimidinone ribosides and analogs which shows anti-tumor properties. It plays as an important role as a reagent for the regioselective desulfation of polysaccharide sulfates. Furthermore, it is used to prepare trimethylsilyl ethers of carbohydrates and alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

• Ampouled under argon

Specifications

Chemical Identifiers

• CAS: 25561-30-2
• Molecular Formula: C8H18F3NOSi2
• Molecular Weight (g/mol): 257.403
• MDL Number: MFCD00008269
• InChI Key: XCOBLONWWXQEBS-GHXNOFRVSA-N
• Synonym: bstfa, n,o-bis trimethylsilyl trifluoroacetamide, acetamide, 2,2,2-trifluoro-o,n-bis trimethylsilyl, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl acetimidate, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl ethanimidate, trimethylsilyl 1z-2,2,2-trifluoro-n-z-trimethylsilyl ethanimidoate #, n,o-bis trimethylsilyl trifluoroacetamide bstfa, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl ethanecarboximidate
• PubChem CID: 9601896
• IUPAC Name: trimethylsilyl (1Z)-2,2,2-trifluoro-N-trimethylsilylethanimidate
• SMILES: C[Si](C)(C)N=C(C(F)(F)F)O[Si](C)(C)C

• Melting Point: -10°C
• Color: Colorless to Yellow
• Density: 0.97 g/mL
• Boiling Point: 145°C to 147°C
• Flash Point: 23°C (73°F)
• Packaging: Ampule
• Refractive Index: 1.384
• Quantity: 5 x 1 g
• UN Number: UN2924
• Beilstein: 3607620
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with chloroform.
• Formula Weight: 257.4
• Physical Form: Liquid
• Chemical Name or Material: N,O-Bis (trimethylsilyl)trifluoroacetamide, With 1% TMCS

Safety and Handling

Hazard Category	H226-H314
Hazard Statement	GHS H Statement H314-H226 Causes severe skin burns and eye damage. Flammable liquid and vapor.
Precautionary Statement	P210-P233-P240-P241-P242-P243-P260-P264b-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, CORROSIVE, N.O.S.
EINECSNumber	247-103-9
TSCA	Yes
storageNote1	Ampouled under argon
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only