N,O-Bis(trimethylsilyl)trifluoroacetamide, 98+%

Catalog No.	Quantity
AAA1203322	100 g
AAA1203309	10 g
AAA1203318	50 g
AAA12033-30	250 g

Catalog No. AAA1203322 Supplier Thermo Scientific Chemicals Supplier No. A1203322

Description

CAS: 25561-30-2 | C8H18F3NOSi2 | 257.403 g/mol

N,O-Bis(trimethylsilyl)trifluoroacetamide is used as a derivatization reagent for gas chromatography and mass-spectrometry analysis of phenolic acids in fruits. It is also used as a reactant in the preparation of pyrimidinone ribosides and analogs which shows anti-tumor properties. It plays as an important role as a reagent for the regioselective desulfation of polysaccharide sulfates. Furthermore, it is used to prepare trimethylsilyl ethers of carbohydrates and alcohols.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,O-Bis(trimethylsilyl)trifluoroacetamide is used as a derivatization reagent for gas chromatography and mass-spectrometry analysis of phenolic acids in fruits. It is also used as a reactant in the preparation of pyrimidinone ribosides and analogs which shows anti-tumor properties. It plays as an important role as a reagent for the regioselective desulfation of polysaccharide sulfates. Furthermore, it is used to prepare trimethylsilyl ethers of carbohydrates and alcohols.

Solubility
Miscible with chloroform.

Notes
Moisture sensitive. Store in cool place. Keep the container tightly closed in a dry and well-ventilated place Incompatible with strong oxidizing agents and strong acids.

Specifications

Chemical Identifiers

• CAS: 25561-30-2
• Molecular Formula: C8H18F3NOSi2
• MDL Number: MFCD00008269
• Synonym: bstfa, n,o-bis trimethylsilyl trifluoroacetamide, acetamide, 2,2,2-trifluoro-o,n-bis trimethylsilyl, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl acetimidate, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl ethanimidate, trimethylsilyl 1z-2,2,2-trifluoro-n-z-trimethylsilyl ethanimidoate #, n,o-bis trimethylsilyl trifluoroacetamide bstfa, trimethylsilyl 2,2,2-trifluoro-n-trimethylsilyl ethanecarboximidate
• PubChem CID: 9601896

• Melting Point: -10°C
• Density: 0.97
• Boiling Point: 145°C to 147°C
• Flash Point: 23°C (73°F)
• Refractive Index: 1.384
• Quantity: 100 g
• UN Number: UN2924
• Beilstein: 3607620
• Sensitivity: Moisture sensitive
• Solubility Information: Miscible with chloroform.
• InChI Key: XCOBLONWWXQEBS-GHXNOFRVSA-N
• SMILES: C[Si](C)(C)N=C(C(F)(F)F)O[Si](C)(C)C
• IUPAC Name: trimethylsilyl (1Z)-2,2,2-trifluoro-N-trimethylsilylethanimidate
• Molecular Weight (g/mol): 257.403
• Formula Weight: 257.4
• Percent Purity: ≥98%
• Chemical Name or Material: N,O-Bis (trimethylsilyl)trifluoroacetamide

Safety and Handling

Hazard Category	H226-H314-H335
Hazard Statement	GHS H Statement H314-H318-H226 Causes severe skin burns and eye damage. Causes serious eye damage. Flammable liquid and vapor.
Precautionary Statement	P210-P233-P235-P240-P241-P242-P243-P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 3; Packing Group: III; Proper Shipping Name: FLAMMABLE LIQUIDS, CORROSIVE, N.O.S.
EINECSNumber	247-103-9
TSCA	No
Recommended Storage	Keep cold; Store under Nitrogen

SDS

RUO – Research Use Only