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N4BP1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501568232
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Catalog No. Quantity
50-156-8232 100 μL
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Catalog No. 50-156-8232 Supplier Bethyl Laboratories, Inc Supplier No. A304628A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.

Specifications

Antigen N4BP1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 1 mg/ml
Conjugate Unconjugated
Formulation phosphate, tris citrate with 0.09% sodium azide; pH 7-8
Gene N4BP1
Gene Accession No. O75113
Gene Alias NEDD4-binding protein 1
Gene Symbols N4BP1
Host Species Rabbit
Immunogen Between 250 and 300
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9683
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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