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N4BP1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A304628A

Encompass_Preferred

Catalog No. 50-156-8232


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Description

Description

The recommended shelf life for this product is 1 year from date of receipt.

Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.
Specifications

Specifications

N4BP1
Polyclonal
Unconjugated
N4BP1
NEDD4-binding protein 1
Rabbit
Antigen affinity chromatography
RUO
9683
4° C
Liquid
Immunoprecipitation, Western Blot
1 mg/ml
phosphate, tris citrate with 0.09% sodium azide; pH 7-8
O75113
N4BP1
Between 250 and 300
100 μL
Primary
Human
Antibody
IgG
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