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N4BP1 Rabbit anti-Human, Polyclonal, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A304628A

Description
The recommended shelf life for this product is 1 year from date of receipt.
Nedd4-binding partner-1 (N4BP1) is a developmentally expressed protein interactor and monoubiquitylation substrate of Nedd4, a HECT domain-containing ubiquitin ligase that mediates ubiquitylation and proteasome degradation of target proteins and may have a fundamental role to play in embryonic processes. N4BP1 can undergo Nedd4-mediated polyubiquitylation and proteosomal degradation. N4BP1 also functions as a negative regulator of AIF4 (also known as ITCH or Atrophin-1), an E3-ubiquitin ligase, by interacting with the second WW domain of AIF4 and impairing ubiquitination of substrates.Specifications
N4BP1 | |
Polyclonal | |
Unconjugated | |
N4BP1 | |
NEDD4-binding protein 1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
9683 | |
4° C | |
Liquid |
Immunoprecipitation, Western Blot | |
1 mg/ml | |
phosphate, tris citrate with 0.09% sodium azide; pH 7-8 | |
O75113 | |
N4BP1 | |
Between 250 and 300 | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
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