NADPH oxidase 4 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS4730R

Catalog No. 50-198-6147

Description

Oxygen sensing is essential for homeostasis in all aerobic organisms. A phagocyte-type oxidase, similar to that responsible for the production of large amounts of reactive oxygen species (ROS) in neutrophil granulocytes, with resultant antimicrobial activity, has been postulated to function in the kidney as an oxygen sensor that regulates the synthesis of erythropoietin in the renal cortex. NOX4 has a role as a redox messenger in the activation of intracellular signaling pathways leading (or contributing) to mitochondriogenesis, cell survival, and differentiation in hematopoietic stem cells. Data suggests that NOX4 provides a novel link between the insulin receptor and the generation of cellular reactive oxygen species that enhances insulin signal transduction.

Specifications

• Antigen: NADPH oxidase 4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Nox4
• Gene Alias: AI648021; BOS_24390; Kidney oxidase-1; Kidney superoxide-producing NADPH oxidase; Kox; KOX1; KOX-1; NADPH oxidase 4; NOX4; Renal NAD(P)H-oxidase; Renox; Superoxide-generating NADPH oxidase 4
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 50507
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q9NPH5
• Gene Symbols: Nox4
• Immunogen: KLH conjugated synthetic peptide derived from human NOX4.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG