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Apexbio Technology LLC Nedaplatin 95734-82-0 25mg

Supplier: Apexbio Technology LLC B198625

Nedaplatin (CAS 95734-82-0) is a platinum-based compound structurally related to cisplatin developed as a DNA-damaging agent It exerts its activity by forming platinum-DNA adducts leading to DNA crosslinking and disruption of DNA replication and transcription processes in tumor cells In cellular assays nedaplatin has demonstrated inhibition of tumor colony formation with an IC50 of 94 M This compound is utilized in biomedical research to investigate mechanisms of DNA damage response and to evaluate anticancer activities of platinum-based chemotherapeutics
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