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  6. NAG-1 Monoclonal Antibody (6D12.H10.E4), Rockland™ 

NAG-1 Monoclonal Antibody (6D12.H10.E4), Rockland™
SDP

Catalog No. p-7191129
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100 μg
25 μL
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Catalog No. Quantity
50-194-3812 100 μg
50-199-1226 25 μL
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Catalog No. 50-194-3812 Supplier Rockland Immunochemicals Supplier No. 200501B07
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Description

Rat Monoclonal Antibody

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. This antibody reacts with the C-terminus of endogenous NAG-1 protein from mouse tissues. A BLAST analysis suggests reactivity with NAG-1 from chimpanzee and macaque based on a 100% homology. Partial reactivity is expected against rat based on an 86% homology with the immunizing sequence. Cross-reactivity with NAG-1 from other sources has not been determined.

Bone morphogenetic proteins (e. g., BMP5, MIM 112265) are members of the transforming growth factor-beta (see TGFB1, MIM 190180) superfamily and regulate tissue differentiation and maintenance. They are synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein.

Specifications

Antigen NAG-1
Applications ELISA, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 6D12.H10.E4
Concentration 1.09 mg/mL
Conjugate Unconjugated
Formulation 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Gdf15
Gene Accession No. Q99988, Q9Z0J7
Gene Alias GDF15; GDF-15; growth differentiation factor 15; Growth/differentiation factor 15; macrophage inhibiting cytokine-1; Macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; Placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; Sbf
Gene Symbols Gdf15
Host Species Rat
Immunogen This Protein-A purified antibody was prepared by repeated immunizations with an MBP-tagged recombinant protein produced in E.coli corresponding to C-term mouse NAG-1 protein. Cross reactivity to MBP is negative.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23886, 9518
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a λ
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