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NAGA Monoclonal Antibody (OTI6F3), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA811239

Encompass_Preferred

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Catalog No. 50-168-3929


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Description

Description

NAGA (N-acetylgalactosaminidase, alpha), also known as alpha-galactosidase B or GALB, is a 411 lysosomal protein belonging to the glycosyl hydrolase 27 family that may exist as a homodimer and plays a critical role in glycolipid breakdown. NAGA encodes alpha-N-acetylgalactosaminidase, a lysosomal enzyme, which cleaves alpha-N-acetylgalactosaminyl groups from glycoconjugates. Mapping to human chromosome 22q13.2, NAGA defects are the cause of an autosomal recessive disorder with three phenotypes, known as Schindler disease (types I, II and III) or NAGA deficiency (types I, II and III). Characterized by neurologic manifestations that range in severity, Schindler disease type I is the most severe form, followed by type III, which may have mild-to-moderate effects. Schindler disease type II, also known as Kanzaki disease, is characterized by mild intellectual impairment and angiokeratoma corporis diffusum.
Specifications

Specifications

NAGA
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P17050
NAGA
Full length human recombit protein of human NAGA produced in HEK293T cell.
100 μL
Primary
Human
Antibody
IgG1
Western Blot
OTI6F3
Unconjugated
NAGA
D22S674, GALB
Mouse
Affinity Chromatography
RUO
4668
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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