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  7. Nalidixic acid, 50 mg/ml in water, sterile-filtered, Thermo Scientific Chemicals

Nalidixic acid, 50 mg/ml in water, sterile-filtered, Thermo Scientific Chemicals

Catalog No. AAJ67194XF
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AAJ67194XF 1 mL
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Catalog No. AAJ67194XF Supplier Thermo Scientific Chemicals Supplier No. J67194XF

Description

Nalidixic acid is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. It is used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent)t DNA supercoiling, and chromosome fragmentation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Nalidixic acid is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. It is used to modulate (inhibit) bacterial DNA gyrase-dependent processes such as DNA polymerization, (ATP-dependent)t DNA supercoiling, and chromosome fragmentation.

Solubility
Soluble in chloroform (50 mg/ml), ethanol (0.9 mg/ml) at 23°C, methanol (1.3 mg/ml) at 23°C, toluene (1.6 mg/ml) at 23°C, DMSO (≥ 6 mg/ml), and solution of carbonates. Fully miscible in water.

Notes
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 389-08-2
Molecular Formula C12H12N2O3
Molecular Weight (g/mol) 232.239
MDL Number MFCD00006884
InChI Key MHWLWQUZZRMNGJ-UHFFFAOYSA-N
Synonym nalidixic acid, nalidixin, nevigramon, nalidixate, uronidix, innoxalon, nalidixan, nalitucsan, sicmylon, unaserus
PubChem CID 4421
ChEBI CHEBI:100147
IUPAC Name 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid
SMILES CCN1C=C(C(=O)C2=C1N=C(C=C2)C)C(=O)O

Specifications

Quantity 1 mL
Solubility Information Soluble in chloroform (50mg/ml),ethanol (0.9mg/ml) at 23°C,methanol (1.3mg/ml) at 23°C,toluene (1.6mg/ml) at 23°C,DMSO (? 6mg/ml),and solution of carbonates. Fully miscible in water.
Physical Form Liquid
Chemical Name or Material Nalidixic acid, 50mg/mL in water, sterile-filtered

Safety and Handling

Hazard Category H317-H334
Precautionary Statement P261-P272-P280g-P285-P302+P352-P304+P341-P333+P313-P342+P311-P363-P501c
EINECSNumber 206-864-7
RTECSNumber QN2885000
TSCA No
storageNote1 -30° to -10°C
Recommended Storage Store at -20°C
SDS

RUO – Research Use Only

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