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Invitrogen™ NLRP6 Polyclonal Antibody
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Catalog No. PIPA560466
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100 μL
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PIPA560466 100 μL
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Catalog No. PIPA560466 Supplier Invitrogen™ Supplier No. PA560466
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GEEPNYPLEL LYCLYETQED AFVRQALCRF PELALQRVRF CRMDVAVLSY CVRCCPAGQA LRLISCRLVA AQEKKKKSLG KRLQASLGGG SSSQGTTKQL PASLLHPLFQ Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 65%.

NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-kappa-B and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NLRP6
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene NLRP6
Gene Accession No. P59044
Gene Alias AI504961; angiotensin II/vasopressin receptor; angiotensin/vasopressin receptor; AVR; CLR11.4; dual angiotensin II/vasopressin receptor; NACHT, leucine rich repeat and PYD containing 6; NACHT, LRR and PYD domains-containing protein 6; NACHT/LRR/pyrin domain-containing protein 6; NALP6; Navr; Navr/Avr; NLR family pyrin domain containing 6; NLR family, pyrin domain containing 6; Nlrp6; Non-angiotensin-vasopressin receptor; Non-AVR; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6; PAN3; Pypaf5; PYRIN-containing APAF1-like protein 5; PYRIN-containing APAF1-like protein 5-like
Gene Symbols NLRP6
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human NALP6. Recombinant protein control fragment (Product #RP-97487).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171389
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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