NANOS3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-3547	150 μL

Catalog No. 50-173-3547 Supplier Proteintech Group Inc Supplier No. 216791AP150UL

Description

Rabbit Polyclonal Antibody

os is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In Drosophila, os represses apoptosis during development to ensure proper germ-line development. Unlike os1 whose expression in mice is dispensable, the os2 and os3 proteins are required for germ cell development. os2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while os3-null PGCs are lost during the migration stage regardless of sex. os2 and os3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of os2 can at least partially replace os3 function in a os3-null background. os3 expression can not rescue os2-null defects.

Specifications

• Antigen: NANOS3
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.33 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: NANOS3
• Gene Accession No.: P60323, P60324
• Gene Alias: os homolog 3, os homolog 3 (Drosophila), NANOS1L, NANOS3, NOS 3, NOS3
• Gene Symbols: os3
• Host Species: Rabbit
• Immunogen: NANOS3 Fusion Protein Ag16014
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 244551, 288909, 342977
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG