Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ Napabucasin

Tocris Bioscience™ Napabucasin
GREENER_CHOICE

Catalog No. 552250
Change view
Click to view available options
Quantity:
10 mg
50 mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
552250 50 mg
552210 10 mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Catalog No. 552250 Supplier Tocris Bioscience™ Supplier No. 5522/50
Only null left
Add to Cart
Add to Cart
This item is not returnable. View return policy

Description

STAT3 inhibitor; also blocks cancer stem cell self-renewal

Napabucasin is a STAT3 inhibitor. Blocks spherogenesis of cancer stem cells (CSC), but not hematopoietic stem cells. Inhibits PaCa-2 xenograft tumor growth in mice, even after cessation of treatment, and decreases population of CSCs in PaCa-2 tumors from treated mice. Also blocks spleen and liver metastases of colon cancer cells in a mouse model.

Specifications

Chemical Name or Material 2-Acetylnaphtho[2,3-b]furan-4,9-dione
CAS 83280-65-3
Quantity 50 mg
Target STAT Inhibitors
Molecular Formula C14H8O4
Formula Weight 240.21
Purity >98%
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.