NAPSA Monoclonal Antibody (OTI3C6), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA808724

Catalog No. 50-168-2329

Description

Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules.

Specifications

• Antigen: NAPSA
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: NAPSA
• Gene Alias: KAP, Kdap, NAP1, NAPA, SNAPA
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9476
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Clone: OTI3C6
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O96009
• Gene Symbols: NAPSA
• Immunogen: Human recombit protein fragment corresponding to amino acids 64-244 of human NAPSA produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a