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Abcam Narciclasine, Rho/LIM kinase/cofilin signaling pathway activator, 1MG

Supplier:  Abcam AB2181101MG

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MW 307.25 Da, Purity >98%. Plant growth regulator originally isolated from Narcissus bulbs. Exhibits antiproliferative and pro-apoptotic effects in carcinoma cells and displays cytotoxic activity against a panel of 60 cancer cell lines (mean IC₅₀ = 47 nM). Activity decreases rate of cell division and increases mitosis duration in vitro. Also modulates the Rho/ROCK/LIM kinase/cofilin pathway; stimulates RhoA activation and induces actin polymerization.

The product is subject to the following: Abcam Restricted Use Statement

Catalog No. 50-267-2827


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